TechnologyCheckLight supplies its customers with innovative methods, testing kits and continuous biomonitors for early warning of drinking water contamination. CheckLight’s solutions are used as critical components of contamination warning systems in order to detect, as early as possible, a wide range of contaminating sources in drinking water, as well as the potential for bacterial re-growth.
Commonly used chemical analyzers can detect and identify a restricted number of substances. Numerous other contaminants that cannot be detected and/or that may have unknown toxic properties. While the detection of chemical substances in environmental samples does not necessarily indicate toxicity or biological hazard, the absence of specific chemicals does not necessarily indicate the absence of toxicity.
Biological early warning systems offer the potential to monitor a wide spectrum of contaminants, even those that escape conventional analytical monitoring. It is difficult, at best, to assess the impact of additive, synergistic, or antagonistic interactions of multiple compounds, even if all compounds are known. Biomonitoring, on the other hand, is primarily a screening tool that can detect the toxic interactions of all constituents of a water sample.
CheckLight’s solutions are based on breakthrough proprietary bioluminescence - based technology. CheckLight utilizes non-pathogenic luminous marine bacteria as sensitive biosensors Biological monitoring (or biomonitoring) that can rapidly indicate changes in water quality.
CheckLight’s technologies are based on the scientific work carried out by Professor Shimon Ulitzur, a world renowned expert in the field of marine bioluminescence who has dedicated over thirty years to researching the field.
CheckLight's ground-breaking technology has produced bioassays which are highly sensitive to very low concentrations of a wide range of contaminants including heavy metals and organic toxicants and provide highly reliable and consistent results, within minutes. CheckLight has succeeded in simplifying the bioassays by providing user-friendly products that can be easily used in either field or laboratory setting and can be stored for long periods.
The ToxScreen test technology was verified by the EPA-ETV as a valid rapid water toxicity test in 2003 and 2006 (version I and II, respectively). While keeping its focus on water quality, the novel methods and technologies developed in the company, can also be implemented as powerful quality control tools in other industries, such as, nanotechnology-based production, pharmaceuticals, food products, and air contamination.
Leveraging on the extensive experience of its R&D team, the company is constantly expanding its IP portfolio. It combines different protection tools including patents, trade marks and trade secrets as well as various contractual protection vehicles.
IP is developed in direct relation to the company's business strategy and derived from it directly, creating significant customer value. A clear example of this is the long term storage capacity of the bacteria which is critical for an on-line bacteria based monitor - this differentiator serves as a clear barrier for competitors, and creates customer value by dramatically increasing the cost effectiveness of our solution.
CheckLight’s IP strategy is multi dimensional - interlacing the interdisciplinary nature of its technology and products, combining IP in each element of the value chain of the company.
ETV verfication — Rapid Toxicity Testing Systems
Bacteria bioluminescence:Luminescent bacteria. http://www.biology.pl/
Bacterial bioluminescence: its control and ecological significance. http://www.ncbi.nlm.nih.gov/
Bioluminescent bacteria: lux genes as environmental biosensors. http://www.scielo.br/
Early warning systemsASCE — Database of commercially available and Emerging Technology Water Monitoring Equipment
Using higher organisms in biological early warning systems for real-time toxicity detection - van der Schalie et al .2001.
Strategic monitoring for the European Water Framework Directive - Ian J. Allan et al. Trends in Analytical Chemistry, Vol. 25, No. 7, 2006. .
Early Warning Monitoring to Detect Hazardous Events in Water Supplies. ILSI report.1999.
Water Security Initiative: Interim Guidance on Planning for Contamination Warning System Deployment.
Technologies and Techniques for Early Warning System to Monitor and Evaluate Drinking Water Quality: State-of-the-Art Review. EPA
Introduction to EPA’S Drinking Water Source Protection Programs.
Low-cost ecotoxicity testing of environmental samples using microbiotests for potential implementation of the Water Framework Directive. K. Wadhia, K. Clive Thompson. Trends in Analytical Chemistry, Vol. 26, No. 4, 2007
Water Monitoring Equipment for Toxic Contaminants Technology Assessment. 2004.
Water Safety Plans Managing drinking-water quality from catchment to consumer. WHO.
ToxScreenSelection of a battery of rapid toxicity sensors for drinking water evaluation van der Schalie et al. Biosensors and Bioelectronics 22 (2006) 18–27.
A Novel and Sensitive Test for Rapid Determination of Water Toxicity. S. Ulitzur, et al. Environmental Toxicology Volume 17, Issue 3 , Pages 291 - 296. 2002.
Biotests and Biosensors in the Analysis of (eco)toxoxicological Risk of Soils Highly Polluted by Cadmium, Lead and Zinc: Bioavailable Fractions cause Toxic Hazard KAHRU et al.
Leachate toxicity. Japan.
On-line real time monitoring - peace of mind? Schreppel et al. 2003.
Pilot river basin case study: The Ribble estuary (UK). Ian Allan. 2005.
SWIFT-WFD- Screening methods for Water data information in support of the implementation of the Water Framework Directive.
The use of field studies to establish the performance of a range of tools for monitoring water quality. B. Roig et al. Trends in Analytical Chemistry, Vol. 26, No. 4, 2007